Through this Request for Proposals (RFP), TRISH seeks to grant data access to proposals that utilize existing EXPAND data to accelerate the generation of evidence addressing HRR risks and deliver insights to support astronaut health and performance during current and future exploration missions. This opportunity specifically invites proposals for secondary analysis of de-identified astronaut health and performance data from EXPAND Essential Measures. Successful proposals will demonstrate how their analysis will meaningfully contribute to NASA risk reduction for human health during spaceflight by, for example, answering a key hypothesis, or filling an important knowledge gap.
This is the first time that TRISH is soliciting requests to use this data for hypothesis-driven research that will further the scientific community’s understanding of space health changes faced during short-duration missions and in a non-governmental astronaut subject population. While no funding will be distributed as a result of this call, TRISH is providing limited access to data by enabling peer review, a requirement for researchers seeking access to EXPAND data.
Eligibility
All categories of United States (U.S) institutions and companies are eligible to submit proposals. Proposers must ensure that their proposal complies with all applicable requirements of the Bulk Data Transfer Rule and the Texas Genomic Act of 2025. Principal Investigators (PIs) may collaborate with universities, the private sector, and federal, state, and local government laboratories. In all such arrangements, the applying entity is expected to be responsible for administering the project according to the management approach presented in the proposal. For our policy on international proposers and institutions, please refer to the FAQ and FAR Supplement.
Selected Proposals Information
This RFP will provide access to EXPAND data in lieu of a monetary grant. Selected investigators will receive a non-monetary award consisting of:
Secure access to the requested de-identified EXPAND datasets, and
Limited technical support (a “data concierge”) to facilitate understanding of data dictionaries and study protocols.
No direct funding will be disbursed to selected proposers under this call. All costs for the research effort (e.g., investigator salary, computing, etc.) must be covered by the proposing team’s institutions or other funding sources. Therefore, no budget is required.
Projects are expected to begin by December 2026, following selection and the signing of any required agreements must occur within 60 days of selection notification. The period of performance for each project will be up to 12 months from the start date, by which time the analysis should be completed and a final report deliverables submitted to TRISH.
2026 EXPAND Data Analysis Request for Proposals
EXPAND Data Analysis Request - Frequently Asked Questions (FAQ)
EXPAND Data Analysis Request - DMP Template
2026 EXPAND Data Analysis Request for Proposals
Through this Request for Proposals (RFP), TRISH seeks to grant data access to proposals that utilize existing EXPAND data to accelerate the generation of evidence addressing HRR risks and deliver insights to support astronaut health and performance during current and future exploration missions. This opportunity specifically invites proposals for secondary analysis of de-identified astronaut health and performance data from EXPAND Essential Measures. Successful proposals will demonstrate how their analysis will meaningfully contribute to NASA risk reduction for human health during spaceflight by, for example, answering a key hypothesis, or filling an important knowledge gap.
This is the first time that TRISH is soliciting requests to use this data for hypothesis-driven research that will further the scientific community’s understanding of space health changes faced during short-duration missions and in a non-governmental astronaut subject population. While no funding will be distributed as a result of this call, TRISH is providing limited access to data by enabling peer review, a requirement for researchers seeking access to EXPAND data.
Eligibility
All categories of United States (U.S) institutions and companies are eligible to submit proposals. Proposers must ensure that their proposal complies with all applicable requirements of the Bulk Data Transfer Rule and the Texas Genomic Act of 2025. Principal Investigators (PIs) may collaborate with universities, the private sector, and federal, state, and local government laboratories. In all such arrangements, the applying entity is expected to be responsible for administering the project according to the management approach presented in the proposal. For our policy on international proposers and institutions, please refer to the FAQ and FAR Supplement.
Selected Proposals Information
This RFP will provide access to EXPAND data in lieu of a monetary grant. Selected investigators will receive a non-monetary award consisting of:
Secure access to the requested de-identified EXPAND datasets, and
Limited technical support (a “data concierge”) to facilitate understanding of data dictionaries and study protocols.
No direct funding will be disbursed to selected proposers under this call. All costs for the research effort (e.g., investigator salary, computing, etc.) must be covered by the proposing team’s institutions or other funding sources. Therefore, no budget is required.
Projects are expected to begin by December 2026, following selection and the signing of any required agreements must occur within 60 days of selection notification. The period of performance for each project will be up to 12 months from the start date, by which time the analysis should be completed and a final report deliverables submitted to TRISH.
2026 EXPAND Data Analysis Request for Proposals
EXPAND Data Analysis Request - Frequently Asked Questions (FAQ)
EXPAND Data Analysis Request - DMP Template